Chandana vishwanatham

   Case 4 31 yr old man with B/L pedal edema with scrotal and penile swelling since 2months https://nairaditya97.blogspot. com/2020/11/31-yr-old-male- with-bl-pedal-edema-with.html? m=1 a) Where are the different anatomical locations of the patient's problems and what are the different etiologic possibilities for them? Please chart out the sequence of events timeline between the manifestations of each of these problems and current outcomes.  1.Patient is a chronic alcoholic which causes wet beri beri(heart failure due to thiamine deficiency) 2.peripheral neuropathy due to thiamine deficiencies Wet beriberi is one of the clinical syndromes associated with thiamine deficiency. Thiamine, in its phosphorylated form thiamine pyrophosphate (TPP), is the precursor for the cofactor of both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, which are both key enzymes of the Krebs cycle. The Krebs cycle is an essential part of aerobic glucose metabolism. A decrease in th...

    Case 4 31 yr old man with B/L pedal edema with scrotal and penile swelling since 2 months https://nairaditya97.blogspot. com/2020/11/31-yr-old-male- with-bl-pedal-edema-with.html? m=1 a) Where are the different anatomical locations of the patient's problems and what are the different etiologic possibilities for them? Please chart out the sequence of events timeline between the manifestations of each of these problems and current outcomes.  1.Patient is a chronic alcoholic which causes wet beri beri(heart failure due to thiamine deficiency) 2.peripheral neuropathy due to thiamine deficiency Wet beriberi is one of the clinical syndromes associated with thiamine deficiency. Thiamine, in its phosphorylated form thiamine pyrophosphate (TPP), is the precursor for the cofactor of both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, which are both key enzymes of the Krebs cycle. The Krebs cycle is an essential part of aerobic glucose metabolism. A decrease in th...

  Case 4 31 yr old man with B/L pedal edema with scrotal and penile swelling since 2 months https://nairaditya97.blogspot. com/2020/11/31-yr-old-male- with-bl-pedal-edema-with.html? m=1 a) Where are the different anatomical locations of the patient's problems and what are the different etiologic possibilities for them? Please chart out the sequence of events timeline between the manifestations of each of these problems and current outcomes.  1.Patient is a chronic alcoholic which causes wet beri beri(heart failure due to thiamine deficiency) 2.peripheral neuropathy due to thiamine deficiency Wet beriberi is one of the clinical syndromes associated with thiamine deficiency. Thiamine, in its phosphorylated form thiamine pyrophosphate (TPP), is the precursor for the cofactor of both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, which are both key enzymes of the Krebs cycle. The Krebs cycle is an essential part of aerobic glucose metabolism. A decrease in the activ...